Abstract
Perioral rhytides (smoker lines) are a troubling concern for many women as they age. This condition results from perioral muscle contraction and genetic predisposition, and is worsened by exposure to harmful external factors such as cigarette smoke and ultraviolet light. Correction of perioral rhytides while maintaining a natural look can be challenging. A topical, cosmeceutical line plumper has been developed for targeted use on fine and deep lines as an adjuvant or cosmetic alternative to injectable therapies.
Skin Active Line Lift Duo has been used by 16 subjects, twice daily for duration of 16 – 24 weeks.
The products were well tolerated and there were no adverse events reported during the study. The two-step, topical, cosmeceutical line plumper provided visible skin plumping effects to reduce the appearance of perioral rhytides. Following chart display the dermatologist grading of improvement on the subjects:
Before and after images revealed visually apparent smoothing of perioral rhytides with a natural appearance.
Conclusion
Dermatologist grading revealed that the two-step, topical cosmeceutical line plumper significantly reduced the appearance of perioral rhytides at 16 and 24 weeks. Clinical photography confirmed a natural-looking improvement to the targeted wrinkle area, which was supported by self-assessment. This data supplements previous clinical study results which showed significant reductions in the appearance of other target wrinkles including, glabellar lines, nasolabial folds, crow’s feet and periocular lines versus a vehicle control. This new, cosmeceutical line treatment diminished the appearance of perioral rhytides and can be used to provide cosmetic improvement for this common aging concern.