A High-Potency, Multimechanism Skin Care Regimen Provides Significant Antiaging Effects: Results From a Double-Blind, Vehicle-Controlled Clinical Trial

Author Patricia K. Farris, MD, Brenda L. Edison, BA et al.
Year 2012
Publication Journal of Drugs in Dermatology


A comprehensive treatment approach including the use of clinically proven topical skin care formulations, provides optimal antiaging effects. A high-strength skin care regimen* was developed to deliver a combination of more than 35% active benefit ingredients, include the alpha hydroxyl acid, glycolic acid, the polyhydroxy acid gluconolactone, maltobionic acid, N-actyl glucosamine, retinol, peptides, antioxidants, and apple stem cell extract. Significant improvement in all parameters of aging was at week 30, and dermal density continued to increase with continuous usage.

*Regimen – the 4 products used in this study are Skin Active Exfoliating Wash, Matrix Support SPF 20, Cellular Restoration and Intensive Eye Therapy


Revive your skin as early as 2 weeks

  • In this study, the 4 products used delivered comprehensive antiaging benefits to photodamaged skin as early as week 2
  • Multiple ingredients in this regimen showed positive influence in the reduction of melanin production, reducing hyperpigmentation on the skin.
  • Clinical photography showed improvement in the visual signs of aging. Fine lines and wrinkles were significantly reduced.
  • Silicone replicas of the crow’s feet area demonstrated improvement in skin texture and reduction in fine lines and wrinkles.


Improvement in fine lines and wrinkles, eyelid tightening, and smoother skin texture observed in both clinical photographs and silicone replicas


Significant improvement in signs of aging after the use of the regimen for 16 and 30 weeks